Ketamine Treatment
in San Antonio

Psychiatrist-guided ketamine therapy for individuals with depression, anxiety, or PTSD who have not responded to traditional treatment.
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Fast-Acting Treatment for Resistant Depression

Ketamine therapy has emerged as a groundbreaking option for adults struggling with depression, anxiety, PTSD, or treatment-resistant conditions. Traditional antidepressants usually take weeks to show results, while ketamine often produces noticeable improvements within hours to days.

At Mental Health Associates San Antonio, our trained clinicians administer and monitor ketamine treatments in a safe, supportive environment, ensuring comfort and effectiveness.

What Is Ketamine and Who Is It For?

Ketamine is a medication originally developed as an anesthetic but has been refined for clinical psychiatric use. It is most commonly used for:

Treatment-resistant depression (TRD)

Major depressive disorder with acute suicidal thoughts

Anxiety disorders and PTSD

Individuals who have not responded to two or more conventional antidepressants

Ketamine therapy is always delivered under the guidance of licensed medical professionals and may be incorporated as part of a comprehensive mental health plan that includes therapy, lifestyle adjustments, and ongoing support.

How Does Ketamine Work?

Ketamine affects the brain differently from standard antidepressants. Research indicates it:

  • Enhances synaptic plasticity, helping the brain form new neural connections
  • Modulates glutamate, a neurotransmitter critical for mood regulation
  • Produces rapid improvements in mood and reductions in suicidal thoughts

This unique method is what allows ketamine to offer faster relief for patients who have struggled with conventional treatments.

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What You Can Expect During Treatment

Ketamine treatment is provided in our clinic under close medical supervision to ensure safety and comfort. Before your session, your provider will review your symptoms, current medications, and prior treatment history to confirm appropriateness and answer any questions.

During treatment, you’ll relax in a quiet, supportive environment while our team monitors your response, blood pressure, and overall comfort. For IV and IM treatments, a designated driver is required, and patients should not drive until the following day.

Intravenous (IV)

Administered through a controlled IV infusion in a clinical setting.

Intramuscular (IM)

Delivered via a precise injection into the muscle under medical supervision.

Spravato (Esketamine)

An FDA-approved intranasal treatment administered in-clinic and monitored by psychiatric providers.
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Conditions Ketamine Can Help With

  • Treatment-Resistant Depression
  • Anxiety & Panic Disorders
  • Post-Traumatic Stress Disorder (PTSD)
  • Bipolar Depression
  • Suicidal Thoughts
  • Obsessive-Compulsive Disorder (OCD)

Accepted Insurance Plans

Simple, Transparent Pricing

IV and IM ketamine treatments are typically not covered by insurance and are offered as self-pay options starting at $300–$400 per session. The Spravato® intranasal treatment is covered by most major insurance plans. Our staff will verify your coverage and explain all options before your first visit.

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FAQ: Ketamine Treatment

How does ketamine help with depression and PTSD?

Ketamine stimulates glutamate activity in the brain, helping repair neural pathways involved in mood and emotion — often providing rapid symptom relief. 

Many patients notice improvement within 24–48 hours after their first or second session, though individual results vary.

Yes. When administered under medical supervision, ketamine is considered safe and well-tolerated. Side effects such as mild dizziness or nausea are temporary and monitored closely.

IV infusions typically last 40–60 minutes, while IM and Spravato® sessions are shorter. 

A typical initial series includes 6–8 treatments, followed by maintenance sessions as recommended by your provider. 

In most cases, yes. Your provider will review your medications to ensure safe and effective coordination.

Not at all. We often combine medication with therapy, TMS, or ketamine treatment for a more holistic approach to mental wellness. 

Take the Next Step In Your Mental Health Care

Ketamine therapy is most effective when integrated into a complete mental health plan. At Mental Health Associates San Antonio, we combine ketamine therapy, Spravato®, TMS, medication management, and ongoing support to help patients achieve long-term relief and stability.

If you’re struggling with depression, anxiety, or treatment-resistant mental health conditions, ketamine may provide the breakthrough you’ve been seeking. Our team is here to guide you through every step.

Contact us today to schedule an evaluation and see if ketamine treatment is right for you.

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Contact Mental Health
Associates San Antonio

Whether you have questions about our treatments, insurance coverage, or want to schedule your first appointment, we’re ready to help.
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    Mental Health Associates San Antonio is a proud member of Privia Medical Group. The best doctors in our community have joined together to form Privia Medical Group (PMG), a multi-specialty, high-performance medical group that puts patients first. Our physicians are united by the mission of providing better, more coordinated care for their patients. To learn more about Privia Medical Group and find other Privia doctors, please visit our website.